MolNFT v1 · #119746 · protein

S. enterica hisa mutant D10G

5G5I: “S. enterica hisa mutant D10G”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.65). MolNFT v1 #119746 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5G5I
Type: protein
Length: 228 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
EC: 5.3.1.16
UniProt: V7IJE3
Ligands: PO4
Pockets: 2 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	(EC 5.3.1.16)	protein	228	40% helix, 24% strand	V7IJE3

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A
EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	461	0.65	0.77	45	PO4
2	54	0.31	0.76	14	empty

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt V7IJE3
Elsewhere: RCSB PDB 5G5I · PDBe 5G5I · UniProt V7IJE3

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