MolNFT v1 · #119642 · protein
Type IV-like competence pilin TTHA1222 from thermus thermophilus
5G2F · Type-IV like pilin TTHA1222: “Type IV-like competence pilin TTHA1222 from thermus thermophilus”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.71). MolNFT v1 #119642 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5G2F
- Type
- protein
- Length
- 246 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type-IV like pilin TTHA1222
- UniProt
- Q5SIZ2
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 20% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Type-IV like pilin TTHA1222 | protein | 86 | 20% helix, 27% strand | Q5SIZ2 |
| C | Type-IV like pilin TTHA1222 | protein | 74 | 20% helix, 26% strand | Q5SIZ2 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 461 | 0.71 | 0.81 | 54 | empty |
| 2 | 97 | 0.34 | 0.74 | 16 | empty |
Interfaces
3 interfaces between chains.
- A–B · 621 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 399 Ų buried · 0 hydrogen bonds · protein-protein
- A–C · 111 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 5G2F · Type IV-like competence pilin TTHA1222 from Thermus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SIZ2
- Elsewhere: RCSB PDB 5G2F · PDBe 5G2F · UniProt Q5SIZ2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.