MolNFT v1 · #119559 · protein
Designed tpr protein M4N delta C (cf I)
5FZR: “Designed tpr protein M4N delta C (cf I)”. X-ray diffraction, 2 pockets (best druggability 0.74). MolNFT v1 #119559 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5FZR
- Type
- protein
- Length
- 424 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Designed tpr protein
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 82% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Designed tpr protein | protein | 107 | 81% helix, 0% strand | — |
| B, D | Designed tpr protein | protein | 105 | 82% helix, 0% strand | — |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 758 | 0.74 | 0.79 | 49 | empty |
| 2 | 722 | 0.69 | 0.77 | 58 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1098 Ų buried · 5 hydrogen bonds · protein-protein
- A–B · 982 Ų buried · 4 hydrogen bonds · protein-protein
- A–D · 529 Ų buried · 6 hydrogen bonds · protein-protein
- B–C · 393 Ų buried · 2 hydrogen bonds · protein-protein
- B–D · 330 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 5FZR · Designed TPR Protein M4N delta C (CF I) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5FZR · PDBe 5FZR
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