MolNFT v1 · #11948 · protein

Solution structure of N-terminal SH3 domain MUTANT(P33G) of murine vav

1K1Z: “Solution structure of N-terminal SH3 domain MUTANT(P33G) of murine vav”. Solution nmr, 1 pocket (best druggability 0.30). MolNFT v1 #11948 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1K1Z
Type: protein
Length: 78 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Vav
UniProt: P27870
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 0% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Vav	protein	78	0% helix, 31% strand	P27870

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.30	0.75	15	empty

Compared structures

1K1Z · Solution structure of N-terminal SH3 domain mutant(P33G) of murine Vav · the same entry in another collection · chain A against A, TM-score 1.00
P27870 · AlphaFold monomer V2.0 prediction for proto-oncogene vav (P27870) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27870
Elsewhere: RCSB PDB 1K1Z · PDBe 1K1Z · UniProt P27870

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