MolNFT v1 · #119381 · protein

Crystal structure of the MEP2 mutant S453D from candida albicans

5FUF · Ammonium transporter: “Crystal structure of the MEP2 mutant S453D from candida albicans”. X-ray diffraction, 6 pockets (best druggability 0.64). MolNFT v1 #119381 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5FUF
Type: protein
Length: 449 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ammonium transporter
UniProt: Q59UP8
Pockets: 6 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ammonium transporter	protein	449	64% helix, 3% strand	Q59UP8

Ligands and binding sites

DMU · Decyl-beta-D-maltopyranoside · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	316	0.64	0.80	49	empty
2	56	0.40	0.81	13	empty
3	56	0.33	0.78	15	empty
4	74	0.30	0.73	17	empty
5	58	0.30	0.75	13	empty

Compared structures

5FUF · Crystal structure of the Mep2 mutant S453D from Candida albicans · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q59UP8
Elsewhere: RCSB PDB 5FUF · PDBe 5FUF · UniProt Q59UP8

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