MolNFT v1 · #119358 · protein
Sulfur sad phasing of CDC23NTERM: data collection with a tailored X- ray beam size at 2.69 a wavelength (4.6 kev)
5FTP · Anaphase-promoting complex subunit 8: “Sulfur sad phasing of CDC23NTERM: data collection with a tailored X- ray beam size at 2.69 a wavelength (4.6…”. X-ray diffraction, 3 pockets (best druggability 0.76). MolNFT v1 #119358 on…
- PDB
- 5FTP
- Type
- protein
- Length
- 472 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anaphase-promoting complex subunit 8
- UniProt
- O94556
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 70% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Anaphase-promoting complex subunit 8 | protein | 230 | 70% helix, 0% strand | O94556 |
| B | Anaphase-promoting complex subunit 8 | protein | 242 | 70% helix, 0% strand | O94556 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 937 | 0.76 | 0.78 | 97 | empty |
| 2 | 63 | 0.32 | 0.75 | 19 | empty |
| 3 | 60 | 0.28 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 2287 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 5FTP · sulfur SAD phasing of Cdc23Nterm: data collection with a tailored X- ray beam size at… · the same entry in another collection · chain A against A, TM-score 1.00
- O94556 · AlphaFold monomer V2.0 prediction for anaphase-promoting complex subunit 8 (O94556) · a predicted model of the same protein · chain B against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O94556
- Elsewhere: RCSB PDB 5FTP · PDBe 5FTP · UniProt O94556
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