MolNFT v1 · #119242 · protein

Crystal structure of the lipoprotein BT2262 from bacteroides thetaiotaomicron

5FQ3 · BT_2262: “Crystal structure of the lipoprotein BT2262 from bacteroides thetaiotaomicron”. X-ray diffraction, 8 pockets (best druggability 0.70). MolNFT v1 #119242 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5FQ3
Type: protein
Length: 796 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BT_2262
UniProt: Q8A5H7
Pockets: 8 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 2% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	BT_2262	protein	199	2% helix, 49% strand	Q8A5H7

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	938	0.70	0.75	75	empty
2	858	0.68	0.74	80	empty
3	278	0.52	0.75	35	empty
4	206	0.50	0.76	26	empty
5	126	0.41	0.75	21	empty

Interfaces

4 interfaces between chains.

A–B · 714 Å² buried · 6 hydrogen bonds · protein-protein
C–D · 709 Å² buried · 7 hydrogen bonds · protein-protein
B–D · 534 Å² buried · 14 hydrogen bonds · protein-protein
A–C · 525 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

5FQ3 · Crystal structure of the lipoprotein BT2262 from Bacteroides thetaiotaomicron · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8A5H7
Elsewhere: RCSB PDB 5FQ3 · PDBe 5FQ3 · UniProt Q8A5H7

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