MolNFT v1 · #11917 · protein

Solution structure of melanoma inhibitory activity protein

1K0X · Melanoma derived growth regulatory protein: “Solution structure of melanoma inhibitory activity protein”. Solution nmr, 2 pockets (best druggability 0.44). MolNFT v1 #11917 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 1K0X
Type: protein
Length: 108 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Melanoma derived growth regulatory protein
UniProt: Q16674
Pockets: 2 · best druggability 0.44

Structure

solution nmr · 1 distinct chain · 3% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Melanoma derived growth regulatory protein	protein	108	3% helix, 39% strand	Q16674

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.44	0.76	23	empty
2	55	0.29	0.75	15	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1K0X · Solution Structure of Melanoma Inhibitory Activity Protein · the same entry in another collection · chain A against A, TM-score 1.00
Q16674 · AlphaFold monomer V2.0 prediction for melanoma-derived growth regulatory protein (Q16674) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16674
Elsewhere: RCSB PDB 1K0X · PDBe 1K0X · UniProt Q16674

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