MolNFT v1 · #118814 · protein

Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0

5FDD · Polymerase acidic PROTEIN,POLYMERASE acidic protein: “Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0”. X-ray diffraction, 3 ligands (4P8, MN, SO4), 1 pocket (best…

PDB: 5FDD
Type: protein
Length: 181 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polymerase acidic PROTEIN,POLYMERASE acidic protein
UniProt: P03433
Ligands: 4P8, MN, SO4
Pockets: 1 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 54% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polymerase acidic PROTEIN,POLYMERASE acidic protein	protein	181	54% helix, 13% strand	P03433

Ligands and binding sites

4P8 · 5-(2-chlorobenzyl)-2-hydroxy-3-nitrobenzaldehyde · ligand · chains A
MN · Manganese (II) ion · metal · chains A
SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	488	0.67	0.78	43	4P8, MN

Compared structures

5FDD · Endonuclease inhibitor 1 bound to influenza strain H1N1 polymerase acidic subunit… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03433
Elsewhere: RCSB PDB 5FDD · PDBe 5FDD · UniProt P03433

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.