MolNFT v1 · #11880 · protein

Cell transformation by the myc oncogene activates expression of a lipocalin: analysis of the gene (Q83) and solution structure of its protein product

1JZU · Lipocalin Q83: “Cell transformation by the myc oncogene activates expression of a lipocalin: analysis of the gene (Q83) and…”. Solution nmr, 3 pockets (best druggability 0.67). MolNFT v1 #11880 on GenesisL1: 3D structure, binding…

PDB: 1JZU
Type: protein
Length: 157 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipocalin Q83
UniProt: Q9I9P7
Pockets: 3 · best druggability 0.67

Structure

solution nmr · 1 distinct chain · 17% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lipocalin Q83	protein	157	17% helix, 48% strand	Q9I9P7

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	428	0.67	0.79	45	empty
2	68	0.51	0.85	26	empty
3	84	0.36	0.75	19	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1JZU · Cell transformation by the myc oncogene activates expression of a lipocalin: analysis of… · the same entry in another collection · chain A against A, TM-score 1.00
Q9I9P7 · AlphaFold monomer V2.0 prediction for extracellular fatty acid- binding protein (Q9I9P7) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I9P7
Elsewhere: RCSB PDB 1JZU · PDBe 1JZU · UniProt Q9I9P7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.