MolNFT v1 · #118791 · protein

Microtubule binding domain of human CEP135

5FCN · Centrosomal protein of 135 kda: “Microtubule binding domain of human CEP135”. X-ray diffraction. MolNFT v1 #118791 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5FCN
Type: protein
Length: 107 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Centrosomal protein of 135 kda
UniProt: Q66GS9

Structure

x-ray diffraction · 2 distinct chains · 95% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Centrosomal protein of 135 kda	protein	53	96% helix, 0% strand	Q66GS9
A	Centrosomal protein of 135 kda	protein	54	94% helix, 0% strand	Q66GS9

Interfaces

1 interface between chains.

B–A · 1327 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

5FCN · microtubule binding domain of human CEP135 · the same entry in another collection · chain B against B, TM-score 1.00
Q66GS9 · AlphaFold monomer V2.0 prediction for centrosomal protein of 135 kda (Q66GS9) · a predicted model of the same protein · chain B against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q66GS9
Elsewhere: RCSB PDB 5FCN · PDBe 5FCN · UniProt Q66GS9

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