MolNFT v1 · #118763 · protein
Crystal structure of rifampin phosphotransferase rph-lm from listeria monocytogenes in complex with ADP and magnesium
5FBS · Phosphoenolpyruvate synthase: “Crystal structure of rifampin phosphotransferase rph-lm from listeria monocytogenes in complex with ADP and…”. X-ray diffraction, 2 ligands (ADP, MG), 11 pockets (best druggability 0.69). MolNFT v1…
- PDB
- 5FBS
- Type
- protein
- Length
- 787 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoenolpyruvate synthase
- Ligands
- ADP, MG
- Pockets
- 11 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoenolpyruvate synthase | protein | 787 | 41% helix, 16% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.69 | 0.85 | 43 | empty |
| 2 | 359 | 0.68 | 0.82 | 42 | MG, ADP |
| 3 | 537 | 0.65 | 0.76 | 47 | empty |
| 4 | 321 | 0.61 | 0.78 | 48 | empty |
| 5 | 59 | 0.53 | 0.87 | 17 | empty |
Compared structures
- 5FBS · Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 5FBS · PDBe 5FBS
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.