MolNFT v1 · #118509 · protein

Activity and crystal structure of francisella novicida udp-N- acetylglucosamine acyltransferase

5F42 · Acyl-[acyl-carrier-protein]--udp-N-acetylglucosamine O…: “Activity and crystal structure of francisella novicida udp-N- acetylglucosamine acyltransferase”. X-ray diffraction, 3 pockets (best druggability 0.77). MolNFT v1 #118509 on…

PDB: 5F42
Type: protein
Length: 552 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acyl-[acyl-carrier-protein]--udp-N-acetylglucosamine O- acyltransferase
EC: 2.3.1.129
UniProt: A0Q7Y0
Pockets: 3 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Acyl-[acyl-carrier-protein]--udp-N-acetylglucosamine O- acyltransferase (EC 2.3.1.129)	protein	276	19% helix, 25% strand	A0Q7Y0

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	534	0.77	0.84	74	empty
2	123	0.40	0.75	25	empty
3	70	0.30	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 1119 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

5F42 · Activity and Crystal Structure of Francisella novicida UDP-N-Acetylglucosamine… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0Q7Y0
Elsewhere: RCSB PDB 5F42 · PDBe 5F42 · UniProt A0Q7Y0

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