MolNFT v1 · #118400 · protein

Cohesin subunit PDS5

5F0N · Cohesin subunit PDS5,COHESIN subunit PDS5, cohesin subunit…: “Cohesin subunit PDS5”. X-ray diffraction, 8 pockets (best druggability 0.69). MolNFT v1 #118400 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5F0N
Type: protein
Length: 1,038 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cohesin subunit PDS5,COHESIN subunit PDS5, cohesin subunit PDS5,KLTH0D07062P,COHESIN…
UniProt: C5DGP8
Pockets: 8 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cohesin subunit PDS5,COHESIN subunit PDS5, cohesin subunit PDS5,KLTH0D07062P,COHESIN subunit PDS5,COHESIN subunit PDS5, cohesin subunit PDS5,KLTH0D07062P,COHESIN subunit PDS5,COHESIN subunit PDS5, cohesin subunit PDS5,KLTH0D07062P,COHESIN subunit PDS5,COHESIN subunit PDS5, cohesin subunit PDS5	protein	1038	69% helix, 0% strand	C5DGP8

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	785	0.69	0.76	83	empty
2	86	0.53	0.84	17	empty
3	174	0.49	0.77	28	empty
4	83	0.46	0.81	20	empty
5	52	0.36	0.79	11	empty

Compared structures

5F0N · Cohesin subunit Pds5 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C5DGP8
Elsewhere: RCSB PDB 5F0N · PDBe 5F0N · UniProt C5DGP8

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