MolNFT v1 · #118385 · protein
Crystal structure of glutathione transferase F7 from populus trichocarpa
5F06 · Glutathione S-transferase family protein: “Crystal structure of glutathione transferase F7 from populus trichocarpa”. X-ray diffraction, 2 ligands (GSH, SO4), 4 pockets (best druggability 0.77). MolNFT v1 #118385 on GenesisL1: 3D…
- PDB
- 5F06
- Type
- protein
- Length
- 426 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutathione S-transferase family protein
- UniProt
- U5GTL0
- Ligands
- GSH, SO4
- Pockets
- 4 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glutathione S-transferase family protein | protein | 213 | 59% helix, 8% strand | U5GTL0 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 392 | 0.77 | 0.86 | 46 | empty |
| 2 | 1147 | 0.72 | 0.75 | 81 | GSH, SO4 |
| 3 | 118 | 0.37 | 0.73 | 21 | empty |
| 4 | 95 | 0.36 | 0.74 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1448 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 5F06 · Crystal structure of glutathione transferase F7 from Populus trichocarpa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt U5GTL0
- Elsewhere: RCSB PDB 5F06 · PDBe 5F06 · UniProt U5GTL0
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