MolNFT v1 · #118373 · protein

Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic acid.

5EZU · Protein A46: “Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in complex with myristic…”. X-ray diffraction, 1 ligand (MYR), 1 pocket (best druggability 0.79). MolNFT v1 #118373 on GenesisL1: 3D…

PDB: 5EZU
Type: protein
Length: 143 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein A46
UniProt: P26672
Ligands: MYR
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 0% helix, 67% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein A46	protein	76	0% helix, 66% strand	P26672
B	Protein A46	protein	67	0% helix, 69% strand	P26672

Ligands and binding sites

MYR · Myristic acid · ligand · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	181	0.79	0.93	24	MYR

Interfaces

1 interface between chains.

A–B · 1348 Å² buried · 36 hydrogen bonds · protein-protein

Compared structures

5EZU · Crystal structure of the N-terminal domain of vaccinia virus immunomodulator A46 in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26672
Elsewhere: RCSB PDB 5EZU · PDBe 5EZU · UniProt P26672

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