MolNFT v1 · #118372 · protein
Peracetylated bovine carbonic anhydrase II
5EZT · Carbonic anhydrase 2: “Peracetylated bovine carbonic anhydrase II”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.51). MolNFT v1 #118372 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5EZT
- Type
- protein
- Length
- 257 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbonic anhydrase 2
- EC
- 4.2.1.1
- UniProt
- P00921
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Carbonic anhydrase 2 (EC 4.2.1.1) | protein | 257 | 16% helix, 30% strand | P00921 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 136 | 0.51 | 0.80 | 23 | empty |
| 2 | 50 | 0.25 | 0.73 | 17 | empty |
Modifications
Observed in the structure: 18 modified (acetylation).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00921
- Elsewhere: RCSB PDB 5EZT · PDBe 5EZT · UniProt P00921
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