MolNFT v1 · #118314 · protein

Crystal structure of glutathione transferase F2 from populus trichocarpa

5EY6 · Phi class glutathione transferase GSTF2: “Crystal structure of glutathione transferase F2 from populus trichocarpa”. X-ray diffraction, 5 pockets (best druggability 0.68). MolNFT v1 #118314 on GenesisL1: 3D structure, binding sites…

PDB: 5EY6
Type: protein
Length: 432 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phi class glutathione transferase GSTF2
EC: 2.5.1.18
UniProt: B9GQ64
Pockets: 5 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 59% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phi class glutathione transferase GSTF2 (EC 2.5.1.18)	protein	215	57% helix, 7% strand	B9GQ64
B	Phi class glutathione transferase GSTF2 (EC 2.5.1.18)	protein	217	61% helix, 6% strand	B9GQ64

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	178	0.68	0.87	36	empty
2	461	0.61	0.75	39	empty
3	299	0.53	0.75	32	empty
4	122	0.41	0.75	20	empty
5	87	0.34	0.74	18	empty

Interfaces

1 interface between chains.

A–B · 1379 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

5EY6 · Crystal structure of glutathione transferase F2 from populus trichocarpa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B9GQ64
Elsewhere: RCSB PDB 5EY6 · PDBe 5EY6 · UniProt B9GQ64

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.