MolNFT v1 · #118138 · protein
Arabidopsis thaliana SAL1
5ESY · SAL1 phosphatase: “Arabidopsis thaliana SAL1”. X-ray diffraction, 19 pockets (best druggability 0.72). MolNFT v1 #118138 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5ESY
- Type
- protein
- Length
- 692 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SAL1 phosphatase
- EC
- 3.1.3.7, 3.1.3.57
- UniProt
- Q42546
- Pockets
- 19 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | SAL1 phosphatase (EC 3.1.3.7, 3.1.3.57) | protein | 346 | 22% helix, 15% strand | Q42546 |
Pockets
19 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 737 | 0.72 | 0.78 | 67 | empty |
| 2 | 499 | 0.70 | 0.80 | 78 | empty |
| 3 | 207 | 0.62 | 0.82 | 31 | empty |
| 4 | 255 | 0.61 | 0.80 | 34 | empty |
| 5 | 165 | 0.60 | 0.82 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 327 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- Q42546 · AlphaFold monomer V2.0 prediction for SAL1 phosphatase (Q42546) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q42546
- Elsewhere: RCSB PDB 5ESY · PDBe 5ESY · UniProt Q42546
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