MolNFT v1 · #118064 · protein
Crystal structure of the ATPase domain of pan from pyrococcus horikoshii
5EQT · Proteasome-activating nucleotidase: “Crystal structure of the ATPase domain of pan from pyrococcus horikoshii”. X-ray diffraction, 2 ligands (ADP, SO4), 1 pocket (best druggability 0.37). MolNFT v1 #118064 on GenesisL1: 3D…
- PDB
- 5EQT
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proteasome-activating nucleotidase
- UniProt
- O57940
- Ligands
- ADP, SO4
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteasome-activating nucleotidase | protein | 249 | 51% helix, 14% strand | O57940 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.37 | 0.77 | 15 | ADP |
Modifications
Observed in the structure: 1 covalent (additive adduct).
Compared structures
- 5EQT · crystal structure of the ATPase domain of PAN from Pyrococcus horikoshii · the same entry in another collection · chain A against A, TM-score 1.00
- O57940 · AlphaFold monomer V2.0 prediction for proteasome-activating nucleotidase (O57940) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O57940
- Elsewhere: RCSB PDB 5EQT · PDBe 5EQT · UniProt O57940
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