MolNFT v1 · #118007 · protein
Structure, regulation, and inhibition of the quorum-sensing signal integrator luxo
5EP4 · Putative repressor protein luxo: “Structure, regulation, and inhibition of the quorum-sensing signal integrator luxo”. X-ray diffraction, 1 ligand (ATP), 1 pocket (best druggability 0.49). MolNFT v1 #118007 on GenesisL1: 3D…
- PDB
- 5EP4
- Type
- protein
- Length
- 253 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative repressor protein luxo
- UniProt
- Q1ZS18
- Ligands
- ATP
- Pockets
- 1 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative repressor protein luxo | protein | 253 | 48% helix, 16% strand | Q1ZS18 |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.49 | 0.78 | 24 | ATP |
Compared structures
- 5EP4 · Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1ZS18
- Elsewhere: RCSB PDB 5EP4 · PDBe 5EP4 · UniProt Q1ZS18
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.