MolNFT v1 · #118004 · protein

Quorum-sensing signal integrator luxo - catalytic domain

5EP1 · Putative repressor protein luxo: “Quorum-sensing signal integrator luxo - catalytic domain”. X-ray diffraction, 2 pockets (best druggability 0.41). MolNFT v1 #118004 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5EP1
Type: protein
Length: 252 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative repressor protein luxo
UniProt: Q1ZS18
Pockets: 2 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative repressor protein luxo	protein	252	46% helix, 15% strand	Q1ZS18

Ligands and binding sites

ACT · Acetate ion · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	103	0.41	0.77	21	ACT
2	54	0.27	0.74	13	ACT

Compared structures

5EP1 · Quorum-Sensing Signal Integrator LuxO - Catalytic Domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q1ZS18
Elsewhere: RCSB PDB 5EP1 · PDBe 5EP1 · UniProt Q1ZS18

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