MolNFT v1 · #117941 · protein
Crystal structure of the N-terminal region of SMU1
5EN8 · Smu-1: “Crystal structure of the N-terminal region of SMU1”. X-ray diffraction, 5 pockets (best druggability 0.36). MolNFT v1 #117941 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5EN8
- Type
- protein
- Length
- 345 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Smu-1
- UniProt
- G5EEG7
- Pockets
- 5 · best druggability 0.36
Structure
x-ray diffraction · 2 distinct chains · 74% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Smu-1 | protein | 172 | 73% helix, 1% strand | G5EEG7 |
| B | Smu-1 | protein | 173 | 75% helix, 1% strand | G5EEG7 |
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.36 | 0.75 | 18 | empty |
| 2 | 87 | 0.34 | 0.75 | 17 | empty |
| 3 | 81 | 0.34 | 0.75 | 18 | empty |
| 4 | 57 | 0.32 | 0.76 | 10 | empty |
| 5 | 63 | 0.30 | 0.74 | 10 | empty |
Interfaces
1 interface between chains.
- A–B · 1360 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G5EEG7
- Elsewhere: RCSB PDB 5EN8 · PDBe 5EN8 · UniProt G5EEG7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.