MolNFT v1 · #117908 · protein
Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(A)R PDZ binding motif
5EM9 · Sorting nexin-27: “Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(A)R PDZ binding motif”. X-ray diffraction. MolNFT v1 #117908 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5EM9
- Type
- protein
- Length
- 102 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sorting nexin-27; Sep-leu-glu-ser-cys-phe
- UniProt
- Q8K4V4
Structure
x-ray diffraction · 2 distinct chains · 13% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-27 | protein | 96 | 14% helix, 40% strand | Q8K4V4 |
| B | Sep-leu-glu-ser-cys-phe | protein | 6 | 0% helix, 67% strand | — |
Interfaces
1 interface between chains.
- A–B · 553 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 5EM9 · Crystal structure of the SNX27 PDZ domain bound to the phosphorylated C-terminal 5HT4(a)R… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8K4V4 · AlphaFold monomer V2.0 prediction for sorting nexin-27 (Q8K4V4) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8K4V4
- Elsewhere: RCSB PDB 5EM9 · PDBe 5EM9 · UniProt Q8K4V4
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