MolNFT v1 · #117893 · protein
Isoform-specific inhibition of sumo-dependent protein-protein interactions
5ELU · Sumo-affirmer-S2B3: “Isoform-specific inhibition of sumo-dependent protein-protein interactions”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #117893 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5ELU
- Type
- protein
- Length
- 166 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sumo-affirmer-S2B3; Small ubiquitin-related modifier 2
- UniProt
- P61956
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sumo-affirmer-S2B3 | protein | 91 | 23% helix, 48% strand | — |
| B | Small ubiquitin-related modifier 2 | protein | 75 | 15% helix, 37% strand | P61956 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 769 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 5ELU · Isoform-specific inhibition of SUMO-dependent protein-protein interactions · the same entry in another collection · chain A against A, TM-score 1.00
- P61956 · AlphaFold monomer V2.0 prediction for small ubiquitin-related modifier 2 (P61956) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P61956
- Elsewhere: RCSB PDB 5ELU · PDBe 5ELU · UniProt P61956
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