MolNFT v1 · #117831 · protein

Structure of dictyostelium discoideum myosin VII MYTH4-ferm MF1 domain

5EJY · Myosin-I heavy chain: “Structure of dictyostelium discoideum myosin VII MYTH4-ferm MF1 domain”. X-ray diffraction, 1 ligand (CL), 8 pockets (best druggability 0.57). MolNFT v1 #117831 on GenesisL1: 3D structure, binding sites and…

PDB: 5EJY
Type: protein
Length: 499 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myosin-I heavy chain
UniProt: Q9U1M8
Ligands: CL
Pockets: 8 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myosin-I heavy chain	protein	499	49% helix, 15% strand	Q9U1M8

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A
15P · Polyethylene glycol (N=34) · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	269	0.57	0.78	33	empty
2	67	0.46	0.83	20	empty
3	88	0.38	0.77	19	empty
4	57	0.38	0.79	15	empty
5	57	0.36	0.79	14	empty

Compared structures

5EJY · Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF1 domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9U1M8 · AlphaFold monomer V2.0 prediction for myosin-I heavy chain (Q9U1M8) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9U1M8
Elsewhere: RCSB PDB 5EJY · PDBe 5EJY · UniProt Q9U1M8

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