MolNFT v1 · #11755 · protein
Crystallization and structure determination of goat lactoferrin at 4.0 resolution: a new form of packing in lactoferrins with a high solvent content in crystals
1JW1: “Crystallization and structure determination of goat lactoferrin at 4.0 resolution: a new form of packing in…”. X-ray diffraction, 1 ligand (FE), 10 pockets (best druggability 0.77). MolNFT v1 #11755 on GenesisL1: 3D structure…
- PDB
- 1JW1
- Type
- protein
- Length
- 689 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lactoferrin
- UniProt
- Q29477
- Ligands
- FE
- Pockets
- 10 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Lactoferrin | protein | 689 | 16% helix, 10% strand | Q29477 |
Ligands and binding sites
- FE · Fe (III) ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 302 | 0.77 | 0.89 | 40 | empty |
| 2 | 286 | 0.75 | 0.88 | 43 | empty |
| 3 | 182 | 0.51 | 0.78 | 20 | empty |
| 4 | 137 | 0.48 | 0.78 | 25 | empty |
| 5 | 81 | 0.40 | 0.78 | 18 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Compared structures
- 1JW1 · Crystallization and structure determination of goat lactoferrin at 4.0 resolution: A new… · the same entry in another collection · chain A against A, TM-score 1.00
- Q29477 · AlphaFold monomer V2.0 prediction for lactotransferrin (Q29477) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q29477
- Elsewhere: RCSB PDB 1JW1 · PDBe 1JW1 · UniProt Q29477
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.