MolNFT v1 · #117441 · protein
Pseudorabies virus nuclear egress complex, PUL31, PUL34
5E8C: “Pseudorabies virus nuclear egress complex, PUL31, PUL34”. X-ray diffraction, 2 ligands (ZN, CL), 6 pockets (best druggability 0.58). MolNFT v1 #117441 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5E8C
- Type
- protein
- Length
- 406 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- UL31; UL34 protein
- UniProt
- G3G955, G3G8R3
- Ligands
- ZN, CL
- Pockets
- 6 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | UL31 | protein | 238 | 45% helix, 21% strand | G3G955 |
| B | UL34 protein | protein | 168 | 25% helix, 30% strand | G3G8R3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.58 | 0.78 | 39 | empty |
| 2 | 210 | 0.53 | 0.77 | 38 | empty |
| 3 | 95 | 0.50 | 0.82 | 23 | empty |
| 4 | 111 | 0.45 | 0.78 | 19 | empty |
| 5 | 86 | 0.42 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1860 Ų buried · 23 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 5E8C · pseudorabies virus nuclear egress complex, pUL31, pUL34 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt G3G955
- Every structure of UniProt G3G8R3
- Elsewhere: RCSB PDB 5E8C · PDBe 5E8C · UniProt G3G955 · UniProt G3G8R3
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