MolNFT v1 · #117387 · protein

Crystal structure of C. elegans lgg-2

5E6N · Protein lgg-2: “Crystal structure of C. elegans lgg-2”. X-ray diffraction, 3 pockets (best druggability 0.44). MolNFT v1 #117387 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5E6N
Type: protein
Length: 221 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein lgg-2
UniProt: Q23536
Pockets: 3 · best druggability 0.44

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein lgg-2	protein	111	33% helix, 24% strand	Q23536
B	Protein lgg-2	protein	110	34% helix, 24% strand	Q23536

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.44	0.75	27	empty
2	128	0.39	0.74	24	empty
3	104	0.37	0.74	21	empty

Interfaces

1 interface between chains.

A–B · 401 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

5E6N · Crystal structure of C. elegans LGG-2 · the same entry in another collection · chain A against A, TM-score 1.00
Q23536 · AlphaFold monomer V2.0 prediction for protein lgg-2 (Q23536) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q23536
Elsewhere: RCSB PDB 5E6N · PDBe 5E6N · UniProt Q23536

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