MolNFT v1 · #117341 · protein

Crystal structure of human SPT16 N-terminal domain

5E5B · Fact complex subunit SPT16: “Crystal structure of human SPT16 N-terminal domain”. X-ray diffraction, 7 pockets (best druggability 0.52). MolNFT v1 #117341 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5E5B
Type: protein
Length: 431 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fact complex subunit SPT16
UniProt: Q9Y5B9
Pockets: 7 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fact complex subunit SPT16	protein	431	40% helix, 22% strand	Q9Y5B9

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.52	0.83	16	empty
2	89	0.49	0.82	21	empty
3	83	0.39	0.78	22	empty
4	87	0.36	0.75	20	empty
5	54	0.34	0.78	12	empty

Compared structures

5E5B · Crystal structure of Human Spt16 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y5B9 · AlphaFold monomer V2.0 prediction for fact complex subunit SPT16 (Q9Y5B9) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y5B9
Elsewhere: RCSB PDB 5E5B · PDBe 5E5B · UniProt Q9Y5B9

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