MolNFT v1 · #117332 · protein

Crystal structure of human CNTN5 FN1-FN3 domains

5E52 · Contactin-5: “Crystal structure of human CNTN5 FN1-FN3 domains”. X-ray diffraction, 1 ligand (PO4), 2 pockets (best druggability 0.38). MolNFT v1 #117332 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5E52
Type: protein
Length: 294 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Contactin-5
UniProt: O94779
Ligands: PO4
Pockets: 2 · best druggability 0.38

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Contactin-5	protein	294	1% helix, 43% strand	O94779

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.38	0.77	19	empty
2	87	0.36	0.76	18	empty

Compared structures

5E52 · Crystal structure of human CNTN5 FN1-FN3 domains · the same entry in another collection · chain A against A, TM-score 1.00
O94779 · AlphaFold monomer V2.0 prediction for contactin-5 (O94779) · a predicted model of the same protein · chain A against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O94779
Elsewhere: RCSB PDB 5E52 · PDBe 5E52 · UniProt O94779

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