MolNFT v1 · #117303 · protein
Crystal structure of beta-lactamase SROS_5706 from streptosporangium roseum
5E43: “Crystal structure of beta-lactamase SROS_5706 from streptosporangium roseum”. X-ray diffraction, 1 ligand (NO3), 1 pocket (best druggability 0.30). MolNFT v1 #117303 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5E43
- Type
- protein
- Length
- 268 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-lactamase
- EC
- 3.5.2.6
- UniProt
- D2ARB3
- Ligands
- NO3
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-lactamase (EC 3.5.2.6) | protein | 268 | 44% helix, 18% strand | D2ARB3 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.30 | 0.73 | 16 | ACT |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 5E43 · Crystal Structure of Beta-lactamase Sros_5706 from Streptosporangium roseum · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D2ARB3
- Elsewhere: RCSB PDB 5E43 · PDBe 5E43 · UniProt D2ARB3
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