MolNFT v1 · #117296 · protein
Crystal structure of phosphatidylinositol-4-phosphate 5-kinase
5E3S · Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha: “Crystal structure of phosphatidylinositol-4-phosphate 5-kinase”. X-ray diffraction, 3 pockets (best druggability 0.63). MolNFT v1 #117296 on GenesisL1: 3D structure, binding…
- PDB
- 5E3S
- Type
- protein
- Length
- 309 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
- UniProt
- Q503I3
- Pockets
- 3 · best druggability 0.63
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | protein | 309 | 36% helix, 25% strand | Q503I3 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 502 | 0.63 | 0.76 | 44 | empty |
| 2 | 225 | 0.49 | 0.75 | 31 | empty |
| 3 | 50 | 0.39 | 0.81 | 19 | empty |
Compared structures
- 5E3S · Crystal structure of Phosphatidylinositol-4-phosphate 5-kinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q503I3
- Elsewhere: RCSB PDB 5E3S · PDBe 5E3S · UniProt Q503I3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.