MolNFT v1 · #11724 · protein

Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 a resolution

1JV4 · Major urinary protein 2: “Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 a resolution”. X-ray diffraction, 2 ligands (TZL, CD), 1 pocket (best druggability 0.83). MolNFT v1 #11724 on GenesisL1: 3D…

PDB: 1JV4
Type: protein
Length: 157 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major urinary protein 2
UniProt: P11589
Ligands: TZL, CD
Pockets: 1 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major urinary protein 2	protein	157	15% helix, 48% strand	P11589

Ligands and binding sites

TZL · 2-(sec-butyl)thiazole · ligand · chains A
CD · Cadmium ion · metal · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	136	0.83	0.99	22	TZL

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1JV4 · Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 A resolution · the same entry in another collection · chain A against A, TM-score 1.00
P11589 · AlphaFold monomer V2.0 prediction for major urinary protein 2 (P11589) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11589
Elsewhere: RCSB PDB 1JV4 · PDBe 1JV4 · UniProt P11589

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.