MolNFT v1 · #117234 · protein

PDZ2 of LNX2 at 277K,SINGLE conformer model

5E21 · Ligand of numb protein X 2: “PDZ2 of LNX2 at 277K,SINGLE conformer model”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #117234 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5E21
Type: protein
Length: 95 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ligand of numb protein X 2
UniProt: Q8N448
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ligand of numb protein X 2	protein	95	15% helix, 37% strand	Q8N448

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	73	0.34	0.76	14	empty

Compared structures

5E21 · PDZ2 of LNX2 at 277K,single conformer model · the same entry in another collection · chain A against A, TM-score 1.00
Q8N448 · AlphaFold monomer V2.0 prediction for ligand of numb protein X 2 (Q8N448) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8N448
Elsewhere: RCSB PDB 5E21 · PDBe 5E21 · UniProt Q8N448

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