MolNFT v1 · #117163 · protein
Structural characterization of intermediate filaments binding domain of desmoplakin
5DZZ: “Structural characterization of intermediate filaments binding domain of desmoplakin”. X-ray diffraction, 3 pockets (best druggability 0.45). MolNFT v1 #117163 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5DZZ
- Type
- protein
- Length
- 489 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Desmoplakin
- UniProt
- P15924
- Pockets
- 3 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Desmoplakin | protein | 489 | 40% helix, 17% strand | P15924 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 94 | 0.45 | 0.79 | 22 | empty |
| 2 | 68 | 0.36 | 0.78 | 20 | empty |
| 3 | 60 | 0.34 | 0.77 | 13 | empty |
Compared structures
- 5DZZ · Structural characterization of intermediate filaments binding domain of desmoplakin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15924
- Elsewhere: RCSB PDB 5DZZ · PDBe 5DZZ · UniProt P15924
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