MolNFT v1 · #11707 · protein

Indole-3-glycerolphosphate synthase from sulfolobus solfataricus in a second orthorhombic crystal form

1JUL · Indole-3-glycerol phosphate synthase: “Indole-3-glycerolphosphate synthase from sulfolobus solfataricus in a second orthorhombic crystal form”. X-ray diffraction, 1 pocket (best druggability 0.71). MolNFT v1 #11707 on GenesisL1: 3D…

PDB: 1JUL
Type: protein
Length: 247 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Indole-3-glycerol phosphate synthase
EC: 4.1.1.48
UniProt: Q06121
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Indole-3-glycerol phosphate synthase (EC 4.1.1.48)	protein	247	40% helix, 16% strand	Q06121

Ligands and binding sites

MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	142	0.71	0.90	29	MES

Compared structures

1JUL · Indole-3-glycerolphosphate synthase from sulfolobus solfataricus in a second orthorhombic… · the same entry in another collection · chain A against A, TM-score 1.00
Q06121 · AlphaFold monomer V2.0 prediction for indole-3-glycerol phosphate synthase (Q06121) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q06121
Elsewhere: RCSB PDB 1JUL · PDBe 1JUL · UniProt Q06121

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