MolNFT v1 · #117035 · protein

Crystal structure of the unliganded geosmin synthase N-terminal domain from streptomyces coelicolor

5DW7 · GERMACRADIENOL/GEOSMIN synthase: “Crystal structure of the unliganded geosmin synthase N-terminal domain from streptomyces coelicolor”. X-ray diffraction, 2 pockets (best druggability 0.74). MolNFT v1 #117035 on GenesisL1: 3D…

PDB: 5DW7
Type: protein
Length: 309 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GERMACRADIENOL/GEOSMIN synthase
EC: 4.2.3.22, 4.2.3.75, 4.1.99.16
UniProt: Q9X839
Pockets: 2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GERMACRADIENOL/GEOSMIN synthase (EC 4.2.3.22, 4.2.3.75, 4.1.99.16)	protein	309	72% helix, 0% strand	Q9X839

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	855	0.74	0.78	65	empty
2	207	0.53	0.77	26	empty

Compared structures

5DW7 · Crystal structure of the unliganded geosmin synthase N-terminal domain from Streptomyces… · the same entry in another collection · chain A against A, TM-score 1.00
Q9X839 · AlphaFold monomer V2.0 prediction for GERMACRADIENOL/GEOSMIN synthase (Q9X839) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X839
Elsewhere: RCSB PDB 5DW7 · PDBe 5DW7 · UniProt Q9X839

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