MolNFT v1 · #116895 · protein
Crystal structure of the G3BP2 NTF2-like domain in complex with a peptide
5DRV · RAS GTPase-activating protein-binding protein 2: “Crystal structure of the G3BP2 NTF2-like domain in complex with a peptide”. X-ray diffraction, 1 pocket (best druggability 0.32). MolNFT v1 #116895 on GenesisL1: 3D structure…
- PDB
- 5DRV
- Type
- protein
- Length
- 139 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAS GTPase-activating protein-binding protein 2; Non-structural protein 3
- UniProt
- Q9UN86, P08411
- Pockets
- 1 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 29% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAS GTPase-activating protein-binding protein 2 | protein | 131 | 31% helix, 41% strand | Q9UN86 |
| B | Non-structural protein 3 | protein | 8 | 0% helix, 25% strand | P08411 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.32 | 0.77 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 524 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 5DRV · Crystal structure of the G3BP2 NTF2-like domain in complex with a peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UN86 · AlphaFold monomer V2.0 prediction for RAS GTPase-activating protein- binding protein 2… · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UN86
- Every structure of UniProt P08411
- Elsewhere: RCSB PDB 5DRV · PDBe 5DRV · UniProt Q9UN86 · UniProt P08411
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