MolNFT v1 · #116723 · protein

Crystal structure of a translational regulator bound to a flagellar assembly factor

5DMB · Flagellar assembly factor fliw: “Crystal structure of a translational regulator bound to a flagellar assembly factor”. X-ray diffraction, 1 pocket (best druggability 0.42). MolNFT v1 #116723 on GenesisL1: 3D structure, binding sites…

PDB: 5DMB
Type: protein
Length: 212 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flagellar assembly factor fliw; Carbon storage regulator homolog
UniProt: A4ISV0, A4ISU9
Pockets: 1 · best druggability 0.42

Structure

x-ray diffraction · 2 distinct chains · 16% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flagellar assembly factor fliw	protein	140	8% helix, 33% strand	A4ISV0
D	Carbon storage regulator homolog	protein	72	32% helix, 25% strand	A4ISU9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.42	0.80	15	empty

Interfaces

1 interface between chains.

A–D · 1455 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

5DMB · Crystal structure of a translational regulator bound to a flagellar assembly factor · the same entry in another collection · chain A against A, TM-score 1.00
A4ISV0 · AlphaFold monomer V2.0 prediction for flagellar assembly factor fliw (A4ISV0) · a predicted model of the same protein · chain A against A, TM-score 0.96
A4ISU9 · AlphaFold monomer V2.0 prediction for translational regulator csra (A4ISU9) · a predicted model of the same protein · chain D against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4ISV0
Every structure of UniProt A4ISU9
Elsewhere: RCSB PDB 5DMB · PDBe 5DMB · UniProt A4ISV0 · UniProt A4ISU9

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