MolNFT v1 · #11659 · protein

Archaeal initiation factor-1A, aif-1A

1JT8 · Probable translation initiation factor 1A: “Archaeal initiation factor-1A, aif-1A”. Solution nmr, 2 pockets (best druggability 0.47). MolNFT v1 #11659 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1JT8
Type: protein
Length: 102 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable translation initiation factor 1A
UniProt: Q57887
Pockets: 2 · best druggability 0.47

Structure

solution nmr · 1 distinct chain · 20% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable translation initiation factor 1A	protein	102	20% helix, 32% strand	Q57887

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	137	0.47	0.77	17	empty
2	67	0.47	0.83	19	empty

Compared structures

1JT8 · Archaeal initiation factor-1A, aif-1A · the same entry in another collection · chain A against A, TM-score 1.00
Q57887 · AlphaFold monomer V2.0 prediction for translation initiation factor 1A (Q57887) · a predicted model of the same protein · chain A against A, TM-score 0.62

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q57887
Elsewhere: RCSB PDB 1JT8 · PDBe 1JT8 · UniProt Q57887

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