MolNFT v1 · #116179 · protein + DNA

Crystal structure of human HSF1 with hse DNA

5D5U · Heat shock element DNA: “Crystal structure of human HSF1 with hse DNA”. X-ray diffraction. MolNFT v1 #116179 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5D5U
Type: protein + DNA
Length: 112 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heat shock element DNA; Heat shock factor protein 1
UniProt: Q00613

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heat shock element DNA	dna	12	—	—
B	Heat shock factor protein 1	protein	100	37% helix, 17% strand	Q00613

Interfaces

1 interface between chains.

A–B · 370 Å² buried · 9 hydrogen bonds · protein-nucleic

Compared structures

5D5U · Crystal structure of human Hsf1 with HSE DNA · the same entry in another collection · chain A against A, TM-score 1.00
Q00613 · AlphaFold monomer V2.0 prediction for heat shock factor protein 1 (Q00613) · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q00613
Elsewhere: RCSB PDB 5D5U · PDBe 5D5U · UniProt Q00613

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