MolNFT v1 · #116030 · protein
Crystal structure of mycobacterium tuberculosis RV0302, form II
5D19 · Tetr family transcriptional regulator: “Crystal structure of mycobacterium tuberculosis RV0302, form II”. X-ray diffraction, 7 pockets (best druggability 0.81). MolNFT v1 #116030 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5D19
- Type
- protein
- Length
- 404 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetr family transcriptional regulator
- UniProt
- A0A045J2D2
- Pockets
- 7 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Tetr family transcriptional regulator | protein | 202 | 74% helix, 0% strand | A0A045J2D2 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 216 | 0.81 | 0.94 | 36 | empty |
| 2 | 82 | 0.76 | 0.97 | 20 | empty |
| 3 | 164 | 0.67 | 0.87 | 31 | empty |
| 4 | 146 | 0.51 | 0.79 | 22 | empty |
| 5 | 102 | 0.46 | 0.80 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 2008 Ų buried · 36 hydrogen bonds · protein-protein
Compared structures
- 5D19 · Crystal structure of Mycobacterium tuberculosis Rv0302, form II · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A045J2D2
- Elsewhere: RCSB PDB 5D19 · PDBe 5D19 · UniProt A0A045J2D2
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