MolNFT v1 · #115974 · protein
Crystal structure of hypd, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase from sinorhizobium meliloti
5CZJ · Dihydrodipicolinate synthase: “Crystal structure of hypd, a 1-pyrroline-4-hydroxy-2-carboxylate deaminase from sinorhizobium meliloti”. X-ray diffraction, 2 pockets (best druggability 0.83). MolNFT v1 #115974 on GenesisL1: 3D…
- PDB
- 5CZJ
- Type
- protein
- Length
- 637 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydrodipicolinate synthase
- EC
- 3.5.4.22
- UniProt
- Q92WT0
- Pockets
- 2 · best druggability 0.83
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydrodipicolinate synthase (EC 3.5.4.22) | protein | 318 | 53% helix, 12% strand | Q92WT0 |
| B | Dihydrodipicolinate synthase (EC 3.5.4.22) | protein | 319 | 54% helix, 12% strand | Q92WT0 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 721 | 0.83 | 0.86 | 95 | empty |
| 2 | 150 | 0.49 | 0.78 | 32 | empty |
Interfaces
1 interface between chains.
- A–B · 1072 Ų buried · 19 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92WT0
- Elsewhere: RCSB PDB 5CZJ · PDBe 5CZJ · UniProt Q92WT0
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