MolNFT v1 · #115958 · protein

Crystal structure of myxoma virus M64

5CZ3 · M64R: “Crystal structure of myxoma virus M64”. X-ray diffraction, 3 pockets (best druggability 0.59). MolNFT v1 #115958 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5CZ3
Type: protein
Length: 299 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: M64R
UniProt: Q9Q8N4
Pockets: 3 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 7% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	M64R	protein	151	7% helix, 46% strand	Q9Q8N4
B	M64R	protein	148	7% helix, 46% strand	Q9Q8N4

Ligands and binding sites

BME · Beta-mercaptoethanol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	364	0.59	0.75	41	empty
2	210	0.47	0.74	19	empty
3	56	0.26	0.73	13	empty

Interfaces

1 interface between chains.

A–B · 445 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 covalent (additive adduct).

Compared structures

5CZ3 · Crystal Structure of Myxoma Virus M64 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Q8N4
Elsewhere: RCSB PDB 5CZ3 · PDBe 5CZ3 · UniProt Q9Q8N4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.