MolNFT v1 · #115695 · protein
Structure of the membrane-binding domain of pneumolysin
5CR8: “Structure of the membrane-binding domain of pneumolysin”. X-ray diffraction, 3 pockets (best druggability 0.46). MolNFT v1 #115695 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5CR8
- Type
- protein
- Length
- 226 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pneumolysin
- UniProt
- A4GRG6
- Pockets
- 3 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 0% helix, 66% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D, A | Pneumolysin | protein | 113 | 0% helix, 66% strand | A4GRG6 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 166 | 0.46 | 0.76 | 25 | empty |
| 2 | 73 | 0.30 | 0.74 | 14 | empty |
| 3 | 60 | 0.28 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- D–A · 449 Ų buried · 4 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A4GRG6
- Elsewhere: RCSB PDB 5CR8 · PDBe 5CR8 · UniProt A4GRG6
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