MolNFT v1 · #11554 · protein
Human cytomegalovirus protease dimer-interface mutant, S225Y
1JQ6 · Assemblin: “Human cytomegalovirus protease dimer-interface mutant, S225Y”. X-ray diffraction, 2 pockets (best druggability 0.34). MolNFT v1 #11554 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1JQ6
- Type
- protein
- Length
- 173 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Assemblin
- EC
- 3.4.21.97
- UniProt
- P16753
- Pockets
- 2 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Assemblin (EC 3.4.21.97) | protein | 173 | 33% helix, 27% strand | P16753 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.34 | 0.75 | 13 | empty |
| 2 | 65 | 0.29 | 0.73 | 12 | empty |
Modifications
Observed in the structure: 3 modified (artifact).
Compared structures
- 1JQ6 · Human cytomegalovirus protease dimer-interface mutant, S225Y · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16753
- Elsewhere: RCSB PDB 1JQ6 · PDBe 1JQ6 · UniProt P16753
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