MolNFT v1 · #115489 · protein
Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium acetobacter aceti, at pH 8.5
5CLF: “Structure of pure (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic bacterium acetobacter…”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.31). MolNFT v1 #115489 on GenesisL1: 3D structure…
- PDB
- 5CLF
- Type
- protein
- Length
- 323 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- N5-carboxyaminoimidazole ribonucleotide mutase
- EC
- 5.4.99.18
- UniProt
- A0A063X4U8
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | N5-carboxyaminoimidazole ribonucleotide mutase (EC 5.4.99.18) | protein | 160 | 46% helix, 16% strand | A0A063X4U8 |
| B | N5-carboxyaminoimidazole ribonucleotide mutase (EC 5.4.99.18) | protein | 163 | 45% helix, 15% strand | A0A063X4U8 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains B
- EDO · 1,2-ethanediol · additive · 4 copies · chains A, B
- ACT · Acetate ion · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.31 | 0.75 | 16 | empty |
| 2 | 78 | 0.30 | 0.73 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1707 Ų buried · 31 hydrogen bonds · protein-protein
Compared structures
- 5CLF · Structure of PurE (N5-carboxyaminoimidazole ribonucleotide mutase) from the acidophilic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A063X4U8
- Elsewhere: RCSB PDB 5CLF · PDBe 5CLF · UniProt A0A063X4U8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.