MolNFT v1 · #115344 · protein

Crystal structure of fox-4 cephamycinase

5CGS · Beta-lactamase: “Crystal structure of fox-4 cephamycinase”. X-ray diffraction, 1 ligand (ZN), 3 pockets (best druggability 0.55). MolNFT v1 #115344 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5CGS
Type: protein
Length: 356 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: Q9L387
Ligands: ZN
Pockets: 3 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	356	41% helix, 23% strand	Q9L387

Ligands and binding sites

ZN · Zinc ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	266	0.55	0.77	45	empty
2	74	0.41	0.80	16	empty
3	94	0.35	0.74	25	empty

Compared structures

5CGS · CRYSTAL STRUCTURE OF Fox-4 cephamycinase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9L387
Elsewhere: RCSB PDB 5CGS · PDBe 5CGS · UniProt Q9L387

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