MolNFT v1 · #115318 · protein
Crystal structure of E. COLI fabi in apo form
5CFZ · Enoyl-[acyl-carrier-protein] reductase [NADH] fabi: “Crystal structure of E. COLI fabi in apo form”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #115318 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5CFZ
- Type
- protein
- Length
- 495 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enoyl-[acyl-carrier-protein] reductase [NADH] fabi
- EC
- 1.3.1.9
- UniProt
- P0AEK4
- Pockets
- 4 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Enoyl-[acyl-carrier-protein] reductase [NADH] fabi (EC 1.3.1.9) | protein | 249 | 49% helix, 17% strand | P0AEK4 |
| B | Enoyl-[acyl-carrier-protein] reductase [NADH] fabi (EC 1.3.1.9) | protein | 246 | 49% helix, 17% strand | P0AEK4 |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 533 | 0.67 | 0.77 | 61 | empty |
| 2 | 308 | 0.57 | 0.76 | 33 | empty |
| 3 | 113 | 0.41 | 0.76 | 22 | empty |
| 4 | 61 | 0.37 | 0.79 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 1707 Ų buried · 43 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AEK4
- Elsewhere: RCSB PDB 5CFZ · PDBe 5CFZ · UniProt P0AEK4
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